Less than two hours after the construction was completed, Yuchao received a reward of 1,500 yuan. He smiled and said that today's income is good, and it is not only his own labor income that makes him happy today. The performance of XCMG's truck crane also makes him very satisfied. “The construction efficiency is high, the engine power is strong, and the work is quick and steady.†Yu Chao said that the operation experience of the XCMG truck crane is very good. Strong alliance He attributed this good operating experience to the heavy-duty-manufacturer engine. In the supporting system of XCMG car cranes, DHC Man Motors occupy an important position. In July this year, the two companies signed a strategic cooperation agreement in Xuzhou, formally establishing their strategic partnership status. The importance of this strategic cooperation to both sides is self-evident. At the signing ceremony, Xugong Chairman Wang Min said: “The development of XCMG is supported by China National Heavy Duty Truck Group. Sinotruk is a peer on our product upgrading road. By." For this strategic cooperation, in 2015, Wang Min and his team visited the headquarters of SINOSTEEL. He was impressed with the achievements of CNHTC in the aspects of product upgrading and technological transformation. In particular, the technical advantages of MAN platform engines provide a good platform for cooperation between the two parties. "With the complementary advantages of Sinotruk and XCMG, and the establishment of a strong, strong, long-term and stable strategic partnership, we can achieve greater sharing of resources and contribute to the future product upgrades, market expansion and brand enhancement of both parties." People said. XCMG and CNHTC have natural advantages. XCMG is a large-scale enterprise group with the largest scale and most complete product lines in China's construction machinery industry. The advantages of CNHTC include vehicle assembly and engine parts assembly capabilities. The world's most advanced engines, pull-type clutches, transmissions, and drive axles are used to make up the highest quality power industry chain in China's heavy truck industry. In particular, after a joint venture with Germany's Mann, the MAN Technology Heavy Duty Truck, Mantech Engine and Axle are more in sync with today's international standards. The values ​​and strategic planning of Sinotruk Mantech Engine and Xugong Group are highly compatible. The Mantech MC series engine from Germany is the latest generation of engines produced by the German company MAN, which is the second largest shareholder of Sinotruk. Its product technology, manufacturing processes and supporting systems are all copied from the German Mann. At present, Mantech's MC series engines have been fully equipped with XG Group's "G1 generation" XCT cranes. The "G1 Generation" truck crane carries the strategic concept of the Xugong Group for the lifting machinery industry. It hopes that the "G1 Generation" will take the lead in bringing the competition in the Chinese construction machinery industry to a high-end new starting point for value-added competition and value creation. According to Wang Gensheng, chairman of CNHTC Hangzhou Engine Sales Co., Ltd. (hereinafter referred to as CNHTC Hangfa Sales Co., Ltd.), CNHTC Mantech's engine is not only powerful and easy to maintain, but it also provides excellent quality of imported engines for OEMs. It also provides convenient service for domestic engines." The cooperation between XCMG and CNHTC dates back to 30 years ago. As the pillar business of Xugong Group, the crane has always participated. From the first generation X6130 engine of Heavy Duty Truck, to the Steyr platform engine, in 2012, the Mantech engine was officially equipped with a 80-ton crane from XCMG. This strategic cooperation covers Xugong’s full range of crane products, ranging from 20 tons to 220 tons. After the test, the technical indicators of the Mantech engine are no less than those of other imported brands, which can save operating costs for users in terms of product reliability and fuel economy. In terms of oil change intervals, the MAN engine has also set a new height in the industry. The MC11 engine can achieve a 1200-hour oil change cycle. Steyr overman In the field of construction machinery, heavy-duty trucks hit the Steyr platform engine, Mantech engine is still in the import phase. In the overall downturn of the construction machinery industry, the engine production of the first half of 2016 was slightly higher than that of the same period of last year. In the automotive sector, the Mantech engine has maintained double-digit growth. According to Shi Guojian, deputy secretary of Party Committee of Heavy Truck Sales Co., Ltd., the company has adjusted the layout of its product structure, and the entire vehicle power platform has shifted to the German Mantech engine, gradually liberalizing the market supply of the Group’s foreign technical engine, and increasing the market of the Mantech Engine Group. The introduction of strength, the formation of the main technical product structure and market structure, the establishment of a brand in the market as soon as possible, the formation of word of mouth in the user. “To gradually establish a high-end brand image in the differentiated product competition, use the product advantages of Mantech Engine to establish market advantages, and guide the heavy truck and construction machinery industry from the existing power represented by Steyr to the advanced power represented by Emmanuel Technology. The transition to achieve power upgrade." Shi Guojian said. The loader market is the largest segment of the construction machinery industry. Heavy-duty trucks have successfully developed the MC07 and D10 common-rail engines for non-road State III emission loaders. It is understood that due to the large number of imported engines used in domestic 7-ton loaders, the high-price service is not timely. Heavy-duty trucks will develop 7-10 tons of MC11/MC13 loader-specific power and make it a benchmark. Earlier this year, Chen Ming, deputy general manager of China National Heavy Duty Trucks Sales Co., Ltd., told the journal that the MC07 engine adopts an appropriate price strategy and uses technological advantages to import the market. The heavy-duty-manchester engine also has the bigger movement in the excavator market, and hopes to break the monopoly pattern that the imported engine unifies the Chinese market. "Adoption of appropriate marketing strategies in the excavator market, the use of technology and price advantage strong import." Shi Guojian said that Sinopharm has successfully developed an exclusive excavator Mantech engine. The construction machinery industry is not a market that can easily profit. The decline in the market for many years has caused the OEMs to feel a burst of chill. The user's living conditions are also not optimistic. The operating rate is not enough. Under the unfavorable situation of rising wage costs, users need a device with high attendance and maintenance costs. Heavy Truck Man Engine is undoubtedly the first choice for users in the current industry situation. Wu Chunjun is a crane self-employed in Zhuji, Zhejiang Province. Within less than two years after entering the crane industry, he has purchased two XCMG cranes equipped with heavy-duty truck engines. The first is the Steyr and the second is the Man Engine. The time difference between the two equipment purchases is less than one year. He paid attention to the official WeChat of Xugong Crane. He knew the strategic cooperation between Sinotruk and XCMG and expressed great interest. At the moment, his engineering capacity is OK. Both machines are working outside. If they are successful, he plans to purchase a larger tonnage Xugong truck crane next year. Wu Chunjun who has this idea does not know that Yu Chao, who has been in the industry for many years, said that the market is not as good as before, but he still has confidence in the industry. Hangzhou, as the venue for the 2016 G20 Summit and the 2022 Asian Games, has a lot of infrastructure to invest in and construction. The amount of future works may increase significantly. He plans to buy another XCMG 55-ton truck crane next year. Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints. It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage and bone destruction, leading to co-morbidities. Despite a variety of therapeutic agents available for treatment, up to 40% of the patients do not respond to current therapies, including biological therapies. The etiology of the disease is mostly unknown; however, the role of JAK as a driver of immune-mediated conditions was discovered, leading to the use of JAK as therapeutic targets for rheumatoid arthritis. To reduce dose-related toxicity (as seen with some pan-JAK inhibitors) without significantly affecting efficacy, more selective JAK1 inhibitors, upadacitinib and [filgotinib], were developed. The FDA approved Upadacitinib in August 2019 for the treatment of adults with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate. In December 2019, it was additionally approved by the European Commission for the same indication in patients with inadequate response or intolerance to one or more DMARDs and can be used as monotherapy or in combination with methotrexate. Upadacitinib is marketed under the brand name RINVOQ™ for oral administration. It is currently being investigated in several clinical trials assessing its therapeutic effectiveness in other inflammatory diseases, such as psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, and atopic dermatitis. Upadacitinib Cas 1201187-44-1,Upadacitinib Cas 1428243-26-8,Upadacitinib Intermediate Cas 1201187-44-1,Upadacitinib Intermediate Cas 1428243-26-8  Shandong Haohong Biotechnology Co., Ltd. , https://www.haohongpharma.com
Mantech Engine
Heavy Truck Mantech Engine Enters Construction Machinery Market
Yu Chao, who was born in 1985, has been in the crane industry for many years. He is an old user of XCMG's truck cranes. Two of the three machines are XCMG's. Now, he runs a rental company called Powerlifting. He is both an owner and a driver. At the end of July, Yu Chaozheng was driving his Xugong truck crane at a construction site in Hangzhou. This is a new device he purchased in October last year, model QY25K5A, equipped with heavy truck MC07.31 Mantech engine .